KMID : 0043319970200030291
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Archives of Pharmacal Research 1997 Volume.20 No. 3 p.291 ~ p.296
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Constituents of the Herb of Isodon excisus var. coreanus
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Kim Ho-Kyoung
Whang Wan Kyunn Kim Il-Hyuk
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Abstract
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The studies were carried out to evaluate the constituents in the aerial part of Isodon excisus var. coreanus (Labiatae). From the aqueous fraction of methanol extract, compound I (-[[3-(3, 4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxy-benzenepropanoic acid), compound II (9-methyl-dihydroferulic acid-4-O-.betha.-D-glucopyranosyl --L- rhamnopyranosyl (1.rarw.4)-.betha.-D-glucopyranoside), compound III (ent-7.alpha., 11,15.betha.-trihydroxy-kaur-16-en-1-O-.betha.-D-glucopyranoside) and compound IV (,3,,23-tetrahydroxy-olean-12 -en-28-oic acid 28-O--D-glucopyranoside) were isolated and identified on the basis of their physicochemical and spectroscopic evidences[IR, FAB(-)MS,COSY and HMBC (Heteronuclear Multiple Bond Connectivity)]. Especially, New compounds II and III were named Isodonin A and Isodonin B respectively.
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KEYWORD
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Isodon excisus var, coreanus Labiatae, Isodonin A, Isodonin B, HMQC, H-H COSY, HMBC, a-[(3[(3, 4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)3, 4-dihydroxybenzenepropanoic acid, 9-Methyl-dihydroferulic acid-4-O-b-D-glucopyranosyl(1-2)a-L-rhamnopyranosyl (1-4)-b-D-glucopyranoside, ent-7a, 11a, 15b-Trihydroxy-kaur-16-en-1-O-b-D-glucopyranoside, 2a, 3b, 7a, 23-tetrahydroxy-olean-12-en-oic acid 28-O-b-D-glucopyranoside
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